Back to Search
Start Over
Autosomal Microsatellite Investigation Reveals Multiple Genetic Components of the Highlanders from Thailand
- Source :
- Genes, Volume 12, Issue 3, Genes, Vol 12, Iss 383, p 383 (2021)
- Publication Year :
- 2021
- Publisher :
- Multidisciplinary Digital Publishing Institute, 2021.
-
Abstract
- The hill tribes of northern Thailand comprise nine officially recognized groups: the Austroasiatic-speaking (AA) Khmu, Htin and Lawa<br />the Hmong-Mien-speaking (HM) IuMien and Hmong<br />and the Sino-Tibetan-speaking (ST) Akha, Karen, Lahu and Lisu. Except the Lawa, the rest of the hill tribes migrated into their present habitats only very recently. The Thai hill tribes were of much interest to research groups focusing on study of cultural and genetic variation because of their unique languages and cultures. So far, there have been several genetic studies of the Thai hill tribes. However, complete forensic microsatellite database of the Thai hill tribes is still lacking. To construct such database, we newly generated 654 genotypes of 15 microsatellites commonly used in forensic investigation that belong to all the nine hill tribes and also non-hill tribe highlanders from northern Thailand. We also combined 329 genotypes from previous studies of northern Thai populations bringing to a total of 983 genotypes, which were then subjected to genetic structure and population relationships analyses. Our overall results indicated homogenous genetic structure within the HM- and Tai-Kadai (TK)-speaking groups, large genetic divergence of the HM-speaking Hmong but not IuMien from the other Thai groups, and genetic heterogeneity within the ST- and AA-speaking groups, reflecting different population interactions and admixtures. In addition to establishing genetic relationships within and among these populations, our finding, which provides a more complete picture of the forensic microsatellite database of the multiple Thai highland dwellers, would not only serve to expand and strengthen forensic investigation in Thailand, but would also benefit its neighboring countries of Laos and Myanmar, from which many of the Thai hill tribes originated and where large populations of these ethnic groups still reside.
- Subjects :
- Male
0301 basic medicine
Genotype
lcsh:QH426-470
Population
Ethnic group
Article
microsatellites
03 medical and health sciences
0302 clinical medicine
Asian People
Genetic variation
hill tribes
Ethnicity
Genetics
Tribe
Humans
030216 legal & forensic medicine
education
Genetics (clinical)
Hmong-Mien
forensic database
education.field_of_study
Genetic heterogeneity
Thailand
Genetic divergence
lcsh:Genetics
030104 developmental biology
Geography
Genetic structure
Microsatellite
Ethnology
Female
Microsatellite Repeats
Subjects
Details
- Language :
- English
- ISSN :
- 20734425
- Database :
- OpenAIRE
- Journal :
- Genes
- Accession number :
- edsair.doi.dedup.....e27d587695d4d1b3c338ce7702b85304
- Full Text :
- https://doi.org/10.3390/genes12030383