Biocatalytic Promiscuity of Lipase in Chemoselective Oxidation of Aryl Alcohols/Acetates: A Unique Synergism of CAL-B and [hmim]Br for the Metal-Free H2O2 Activation

A unique synergistic combination of lipase and ionic liquid [hmim]Br is reported for metal-free H(2)O(2) activation, which is the first example of biocatalytic promiscuity of CAL-B for chemoselective oxidation of aryl alcohols/acetates. The catalytic system exhibits excellent functional group compatibility under neutral conditions besides reusability up to ten cycles thereby making the process economically and environmentally viable.