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Ticlopidine and clopidogrel, sometimes combined with aspirin, only minimally increase the surgical risk in renal transplantation: a case-control study
- Source :
- Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 29(2)
- Publication Year :
- 2013
-
Abstract
- BACKGROUND: Patients undergoing kidney transplantation are sometimes being treated with antiplatelet agents such as ticlopidine or clopidogrel. Some teams refuse to wait-list these patients for fear of bleeding during transplant surgery. METHODS: We retrospectively reviewed the records of 702 adult patients with a kidney transplant alone between 2000 and 2010. Nineteen (2.7%) patients were taking clopidogrel or ticlopidine when called in for transplantation. Furthermore, 10 of these 19 patients were also taking low-dose aspirin (ASA). We compared the risk of bleeding peri- and postoperatively, and the occurrence of cardiovascular complications within 30 days after renal transplantation between 19 cases and 39 controls randomly selected within the cohort. RESULTS: Platelets were administered to 7 cases (37%) versus 0 controls (P
- Subjects :
- Male
Risk
medicine.medical_specialty
Ticlopidine
Time Factors
Blood Loss, Surgical
Postoperative Complications
Risk Factors
medicine
Journal Article
Humans
cardiovascular diseases
Survival rate
Kidney transplantation
Retrospective Studies
Transplantation
Aspirin
Dose-Response Relationship, Drug
business.industry
Research Support, Non-U.S. Gov't
Incidence
Graft Survival
Retrospective cohort study
Middle Aged
Clopidogrel
medicine.disease
Prognosis
Kidney Transplantation
Surgery
Survival Rate
surgical procedures, operative
Nephrology
Anesthesia
Case-Control Studies
Platelet aggregation inhibitor
Kidney Failure, Chronic
Drug Therapy, Combination
Female
business
Platelet Aggregation Inhibitors
circulatory and respiratory physiology
medicine.drug
Follow-Up Studies
Subjects
Details
- ISSN :
- 14602385
- Volume :
- 29
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
- Accession number :
- edsair.doi.dedup.....e2396a51421b5659dd3ee579faa1492d