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Ticlopidine and clopidogrel, sometimes combined with aspirin, only minimally increase the surgical risk in renal transplantation: a case-control study

Authors :
Claude Sadis
Judith Racapé
Lidia Ghisdal
Alain Le Moine
M Wissing
Annick Massart
Dimitri Mikhalski
Daniel Abramowicz
Nilufer Broeders
Ahmed Benahmed
Vincent Donckier
Mireille N Kianda
Anh Dung Hoang
Philippe Madhoun
Anne Lemy
Basic (bio-) Medical Sciences
Source :
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 29(2)
Publication Year :
2013

Abstract

BACKGROUND: Patients undergoing kidney transplantation are sometimes being treated with antiplatelet agents such as ticlopidine or clopidogrel. Some teams refuse to wait-list these patients for fear of bleeding during transplant surgery. METHODS: We retrospectively reviewed the records of 702 adult patients with a kidney transplant alone between 2000 and 2010. Nineteen (2.7%) patients were taking clopidogrel or ticlopidine when called in for transplantation. Furthermore, 10 of these 19 patients were also taking low-dose aspirin (ASA). We compared the risk of bleeding peri- and postoperatively, and the occurrence of cardiovascular complications within 30 days after renal transplantation between 19 cases and 39 controls randomly selected within the cohort. RESULTS: Platelets were administered to 7 cases (37%) versus 0 controls (P

Details

ISSN :
14602385
Volume :
29
Issue :
2
Database :
OpenAIRE
Journal :
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
Accession number :
edsair.doi.dedup.....e2396a51421b5659dd3ee579faa1492d