Back to Search
Start Over
The Rising Incidence of Type 1 Diabetes Mellitus and the Role of Environmental Factors - Three Decade Experience in a Primary Care Health Center in Saudi Arabia
- Source :
- Journal of Pediatric Endocrinology and Metabolism. 23
- Publication Year :
- 2010
- Publisher :
- Walter de Gruyter GmbH, 2010.
-
Abstract
- Background: The incidence of type 1 diabetes has been increasing all over the world including Saudi Arabia and environmental factors have been suggested to play an important role in its etiology. Objective: The aim of this study was to evaluate if there are any contributory roles of various environmental factors in the rising incidence of type 1 diabetes in children in the Eastern Province of Saudi Arabia. Methods: We conducted a retrospective study of Saudi Arab subjects (n = 119) diagnosed between 1980 and 2009 with type 1 diabetes and these subjects were classified to six groups on the basis of the onset of diabetes. Results: 119 subjects (61 boys and 58 girls) with confirmed diagnosis of type 1 diabetes met the study eligibility criteria. 89 children (74%) presented with ketoacidosis. The mean age of onset was 4 3/4 years for Group II and age of onset increased to above 8 years on subsequent years. Excessive weight gain was noted in all study groups. No etiological influences of maternal age at birth, birth order, birth weight, early introduction of cow's milk and cereals, infections and vaccines as well as nitrate levels in drinking water were noted in any of the groups. The predicted doubling of diabetes in young children below 5 years as in previous studies was not found in our study. Conclusions: The rising incidence of type 1 diabetes over the last 30 years is not proved to have been influenced by various environmental factors.
- Subjects :
- Adult
Male
medicine.medical_specialty
Pediatrics
Adolescent
Endocrinology, Diabetes and Metabolism
Birth weight
Saudi Arabia
Weight Gain
Body Mass Index
Endocrinology
Pregnancy
Risk Factors
Diabetes mellitus
Epidemiology
medicine
Humans
Age of Onset
Child
Vaccines
Type 1 diabetes
business.industry
Incidence
Incidence (epidemiology)
Infant, Newborn
Infant
Retrospective cohort study
medicine.disease
Diet
Birth order
Diabetes Mellitus, Type 1
Virus Diseases
Child, Preschool
Pediatrics, Perinatology and Child Health
Environmental Pollutants
Female
Age of onset
business
Maternal Age
Subjects
Details
- ISSN :
- 21910251 and 0334018X
- Volume :
- 23
- Database :
- OpenAIRE
- Journal :
- Journal of Pediatric Endocrinology and Metabolism
- Accession number :
- edsair.doi.dedup.....e2011359cf69a656162bb547ae75a8db