Back to Search
Start Over
Image-Guided Intensity-Modulated Radiation Therapy for IgG4-Related Ophthalmic Disease
- Source :
- Case Reports in Ophthalmological Medicine, Case Reports in Ophthalmological Medicine, Vol 2020 (2020)
- Publication Year :
- 2020
- Publisher :
- Hindawi, 2020.
-
Abstract
- Background. IgG4-related ophthalmic disease is a rare, newly recognized entity with high failure rates on first-line therapy of systemic corticosteroids and no other proven management options. Case Presentation. Here, we present the clinical course of a patient with IgG4 ophthalmic disease who achieved a favorable response from radiotherapy. Our patient initially presented with a history of recurrent painful flares of orbital inflammation, a pathologic diagnosis follicular lymphoid hyperplasia from a right lacrimal gland biopsy, and MRI imaging noting expansion of the lateral rectus muscle of the right eye. Initial treatment with dacryoadenectomy and multiple courses of corticosteroids failed to keep his symptoms at bay. Further evaluation revealed florid IgG4 staining. In this context, he was evaluated for image-guided intensity-modulated radiotherapy (IG-IMRT) to the orbit to 20 Gy in 10 fractions. His ophthalmic symptoms resolved. Conclusions. This treatment experience suggests radiotherapy may be a favorable option for symptom relief in patients with IgG4-related ophthalmic disease not controlled by corticosteroids.
- Subjects :
- 030203 arthritis & rheumatology
medicine.medical_specialty
medicine.diagnostic_test
business.industry
medicine.medical_treatment
Lateral rectus muscle
Context (language use)
Case Report
General Medicine
Intensity-modulated radiation therapy
RE1-994
Lymphoid hyperplasia
Radiation therapy
03 medical and health sciences
Ophthalmology
0302 clinical medicine
medicine.anatomical_structure
Biopsy
030221 ophthalmology & optometry
medicine
Radiology
medicine.symptom
Ophthalmic disease
business
Orbit (anatomy)
Subjects
Details
- Language :
- English
- ISSN :
- 20906730 and 20906722
- Volume :
- 2020
- Database :
- OpenAIRE
- Journal :
- Case Reports in Ophthalmological Medicine
- Accession number :
- edsair.doi.dedup.....e1f45b22344930e2b9e5688103e84731