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A randomized controlled clinical study of periodontal tissue regeneration using an extracellular matrix-based resorbable membrane in combination with a collagenated bovine bone graft in intrabony defects
- Source :
- Journal of Periodontal & Implant Science
- Publication Year :
- 2017
- Publisher :
- Korean Academy of Periodontology, 2017.
-
Abstract
- Purpose The purpose of this study was to investigate the feasibility of regenerative therapy with a collagenated bone graft and resorbable membrane in intrabony defects, and to evaluate the effects of the novel extracellular matrix (ECM)-based membrane clinically and radiologically. Methods Periodontal tissue regeneration procedure was performed using an ECM-based resorbable membrane in combination with a collagenated bovine bone graft in intrabony defects around the teeth and implants. A novel extracellular matrix membrane (NEM) and a widely-used membrane (WEM) were randomly applied to the test group and the control group, respectively. Cone-beam computed tomography images were obtained on the day of surgery and 6 months after the procedure. Alginate impressions were taken and plaster models were made 1 week and 6 months postoperatively. Results The quantity of bone tissue, the dimensional changes of the surgically treated intrabony defects, and the changes in width and height below the grafted bone substitutes showed no significant difference between the test and control groups at the 6-month examination. Conclusions The use of NEM for periodontal regeneration with a collagenated bovine bone graft showed similar clinical and radiologic results to those obtained using WEM.<br />Graphical Abstract
- Subjects :
- Periodontal tissue
Bone substitutes
Guided tissue regeneration
business.industry
Regeneration (biology)
Cone-beam computed tomography
Dentistry
030206 dentistry
Bone tissue
Bone regeneration
Extracellular matrix
Clinical study
03 medical and health sciences
Bovine bone
0302 clinical medicine
medicine.anatomical_structure
Resorbable membranes
Three-dimensional imaging
Periodontics
Medicine
Oral Surgery
business
030217 neurology & neurosurgery
Research Article
Subjects
Details
- Language :
- English
- ISSN :
- 20932286 and 20932278
- Volume :
- 47
- Issue :
- 6
- Database :
- OpenAIRE
- Journal :
- Journal of Periodontal & Implant Science
- Accession number :
- edsair.doi.dedup.....e157f424d001006780b7a6a1f99c9957