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Does transcutaneous electrical nerve stimulation have an antipruritic effect in lichen planus? A randomized clinical trial
- Source :
- Clinical and Experimental Dermatology. 44:252-256
- Publication Year :
- 2018
- Publisher :
- Oxford University Press (OUP), 2018.
-
Abstract
- Lichen planus (LP) is a moderately prevalent inflammatory disorder that affects the skin and the oral mucosa, leading to a characteristic appearance and causing severe itching.To assess the potency of transcutaneous electrical nerve stimulation (TENS) as an antipruritic line of treatment in patients with LP.We enrolled 30 patients with LP who had a history of recurrent relapses of confined pruritus forcing them to scratch or rub the affected area intensively. Patients were treated with TENS three times per week for 4 weeks. Severity of itching was estimated by visual analogue scale (VAS) and Dermatology Life Quality Index (DLQI).There was a statistically significant decline in mean VAS score at weeks 2 and 4 of treatment compared with baseline (P 0.05, with 74% of participants having an improvement of 50%. Significant improvement in itching intensity also resulted in better quality of life, as there was also a significant reduction in median DLQI at weeks 2 and 4 of therapy compared with baseline (P 0.05), with 65% of patients having an improvement of 50% in median DLQI score.TENS may be an alternative safe treatment for LP-induced itching.
- Subjects :
- Adult
Male
medicine.medical_specialty
Visual Analog Scale
Visual analogue scale
Dermatology
Severity of Illness Index
Transcutaneous electrical nerve stimulation
law.invention
030207 dermatology & venereal diseases
03 medical and health sciences
0302 clinical medicine
Randomized controlled trial
Recurrence
law
Humans
Medicine
Oral mucosa
skin and connective tissue diseases
Antipruritic
business.industry
Antipruritic Effect
Lichen Planus
Dermatology Life Quality Index
Middle Aged
Treatment Outcome
medicine.anatomical_structure
030220 oncology & carcinogenesis
Quality of Life
Transcutaneous Electric Nerve Stimulation
Itching
Female
medicine.symptom
business
medicine.drug
Subjects
Details
- ISSN :
- 03076938
- Volume :
- 44
- Database :
- OpenAIRE
- Journal :
- Clinical and Experimental Dermatology
- Accession number :
- edsair.doi.dedup.....e0f2fe84d36d844001a8599c862a5817