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Correlation between clinical syndromes and neuropsychological tasks in unmedicated patients with recent onset schizophrenia
- Source :
- Psychiatry Research. 113:83-92
- Publication Year :
- 2002
- Publisher :
- Elsevier BV, 2002.
-
Abstract
- The aim of this study is to circumscribe the cognitive deficits according to schizophrenic syndromes in a population of sub-acute untreated patients. We have studied the cross-sectional correlation between cognitive deficits and schizophrenic symptoms, in a group of 24 untreated patients (including 17 neuroleptic-naive patients) with recent onset of the disease. A task of alertness, a working memory (WM) test (including two levels of difficulty) and an abbreviated version of the Wisconsin Card Sorting Test (WCST) were selected. WM deficits and poor performance on the WCST were highly correlated with disorganized symptoms, modestly with the positive syndrome and not with the negative syndrome. Thus, disorganized symptoms, more than any other, appear to be related to the impairment of executive function and WM in recent onset unmedicated patients with schizophrenia.
- Subjects :
- Adult
Male
Psychosis
medicine.medical_specialty
Population
Neuropsychological Tests
Audiology
behavioral disciplines and activities
Wisconsin Card Sorting Test
Neuropsychologia
Reaction Time
medicine
Humans
education
Psychiatry
Biological Psychiatry
Memory Disorders
education.field_of_study
Schizophrenia, Disorganized
Working memory
Thought disorder
Neuropsychology
Cognition
medicine.disease
Psychiatry and Mental health
Cross-Sectional Studies
Acute Disease
Female
medicine.symptom
Cognition Disorders
Psychology
Subjects
Details
- ISSN :
- 01651781
- Volume :
- 113
- Database :
- OpenAIRE
- Journal :
- Psychiatry Research
- Accession number :
- edsair.doi.dedup.....e0cadfe5e2eab737ef46447539610e92