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Support for selection of a methamphetamine cleanup standard in Colorado
- Source :
- Regulatory toxicology and pharmacology : RTP. 48(1)
- Publication Year :
- 2006
-
Abstract
- Methamphetamine production for illicit use occurs in makeshift labs and is associated with the release of numerous chemicals, including methamphetamine residues. These methamphetamine residues may pose a health risk to residents who reoccupy these structures after property seizures. Several states have established technology-based cleanup standards for methamphetamine, but none have examined the health-protectiveness of these standards. In response to Colorado House Bill 04-1182, exposure intakes correlated with three technology-based standards were calculated for various groups of individuals. Intakes were assessed for a 1-year-old infant, 6-year-old child, and a female of childbearing age. Exposure intakes were compared to toxicity reference values developed from developmental endpoints following methamphetamine exposure from the available literature. Uncertainty factors were applied to the lowest adverse effect levels observed in these studies to arrive at the toxicity reference values. These reference values were greater than the calculated intakes from each proposed technology standard, suggesting that all of the proposed standards would be protective of human health exposure. The cost and practicality of attaining each of the proposed standards was also factored into the decision making process. In their final regulation (6 CCR 1014-3), the CDPHE selected 0.5 μg/100 cm 2 as the final cleanup standard for methamphetamine residues.
- Subjects :
- Adult
Colorado
business.industry
Infant
General Medicine
Environmental Exposure
Methamphetamine
Toxicology
Human health
Adverse health effect
Reference Values
Environmental health
Reference values
Childbearing age
medicine
Humans
Female
Health risk
business
Risk assessment
Child
Environmental Health
Environmental Restoration and Remediation
medicine.drug
Subjects
Details
- ISSN :
- 02732300
- Volume :
- 48
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Regulatory toxicology and pharmacology : RTP
- Accession number :
- edsair.doi.dedup.....e0b67e9807c334e16a0103dc49ab1761