Back to Search
Start Over
Crossed cerebellar diaschisis in acute ischemic stroke: Impact on morphologic and functional outcome
- Publication Year :
- 2017
- Publisher :
- SAGE Publications, 2017.
-
Abstract
- Crossed cerebellar diaschisis (CCD) is the phenomenon of hypoperfusion and hypometabolism of the contralateral cerebellar hemisphere caused by dysfunction of the related supratentorial region. Our aim was to analyze its influence on morphologic and functional outcome in acute ischemic stroke. Subjects with stroke caused by a large vessel occlusion of the anterior circulation were selected from an initial cohort of 1644 consecutive patients who underwent multiparametric CT including whole-brain CT perfusion. Two experienced readers evaluated the posterior fossa in terms of CCD absence (CCD−) or presence (CCD+). A total of 156 patients formed the study cohort with 102 patients (65.4%) categorized as CCD− and 54 (34.6%) as CCD+. In linear and logistic regression analyses, no significant association between CCD and final infarction volume (β = −0.440, p = 0.972), discharge mRS ≤ 2 (OR = 1.897, p = 0.320), or 90-day mRS ≤ 2 (OR = 0.531, p = 0.492) was detected. CCD+ patients had larger supratentorial cerebral blood flow deficits (median: 164 ml vs. 115 ml; p = 0.001) compared to CCD−patients. Regarding complications, CCD was associated with a higher rate of parenchymal hematomas (OR = 4.793, p = 0.035). In conclusion, CCD is frequently encountered in acute ischemic stroke caused by large vessel occlusion of the anterior circulation. CCD was associated with the occurrence of parenchymal hematoma in the ipsilateral cerebral infarction but did not prove to significantly influence patient outcome.
- Subjects :
- Male
medicine.medical_specialty
Infarction
Perfusion scanning
030218 nuclear medicine & medical imaging
Brain Ischemia
Cohort Studies
03 medical and health sciences
0302 clinical medicine
Hematoma
Cerebellar Diseases
Recurrence
Cerebellar hemisphere
Internal medicine
Medicine
Humans
Thrombolytic Therapy
Stroke
Neuroradiology
Aged
Retrospective Studies
Aged, 80 and over
business.industry
Cerebral infarction
urogenital system
Original Articles
Middle Aged
medicine.disease
equipment and supplies
Prognosis
Treatment Outcome
Neurology
Cerebral blood flow
Cranial Fossa, Posterior
Cerebrovascular Circulation
Cardiology
Female
Neurology (clinical)
Cardiology and Cardiovascular Medicine
business
Tomography, X-Ray Computed
030217 neurology & neurosurgery
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....e07f79a024c44470d22574ba7325e572