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Targeting Parallel Topology of G-Quadruplex Structures by Indole- Fused Quindoline Scaffolds
- Source :
- Biochemistry. 61(22)
- Publication Year :
- 2022
-
Abstract
- Preferential stabilization of G-quadruplex (G4) structures using small-molecule ligands has emerged as an effective approach to develop anticancer drugs. Herein, we report the synthesis of three indole-fused quindoline derivatives with varying lengths of side chains (
- Subjects :
- G-Quadruplexes
Indoles
Quinolines
Ligands
Biochemistry
Subjects
Details
- ISSN :
- 15204995
- Volume :
- 61
- Issue :
- 22
- Database :
- OpenAIRE
- Journal :
- Biochemistry
- Accession number :
- edsair.doi.dedup.....e071d8965b6cb577e0c38dbf7394e24a