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Perfluoroalkyl acids and their isomers, diabetes, anemia, and albuminuria: Variabilities with deteriorating kidney function
- Source :
- Ecotoxicology and Environmental Safety, Vol 208, Iss, Pp 111625-(2021)
- Publication Year :
- 2020
-
Abstract
- Data for US adults aged ≥20 years from National Health and Nutrition Examination Survey for the years 2003–2014 were analyzed to evaluate how adjusted (N = 8481) and unadjusted (N = 9080) levels of selected perfluoroalkyl acids (PFAA) vary across the different stages of glomerular function (GF) among those who did not have diabetes, anemia, or albuminuria as compared to those who had diabetes only, anemia only, and albuminuria only. PFAAs selected for analyses were: perfluorooctanoic acid (PFOA), perfluorooctane sulfonic acid (PFOS), perfluorodecanoic acid (PFDA), perfluorohexane sulfonic acid (PFHxS), and perfluorononanoic acid (PFNA). Irrespective of GF stage, there was no noticeable evidence to suggest that adjusted levels of PFAA for those with diabetes only are any lower than those with no diabetes, no anemia, and no albuminuria. Those who had anemia only were found to have lower adjusted levels of at least PFOA, PFOS, PFDA, and PFHxS than those who had no diabetes, no anemia, and no albuminuria. These results were seen in the presence (eGFR 90 mL/min/1.73 m2), GF-2 (60 ≤ eGFR ≤ 90 mL/min/1.73 m2), and GF-3B/4 (15
- Subjects :
- Male
Health, Toxicology and Mutagenesis
0211 other engineering and technologies
02 engineering and technology
010501 environmental sciences
urologic and male genital diseases
Kidney
01 natural sciences
Environmental pollution
Perfluorononanoic acid
chemistry.chemical_compound
GE1-350
Fluorocarbons
Diabetes
Fatty Acids
Anemia
General Medicine
Middle Aged
Nutrition Surveys
Pollution
female genital diseases and pregnancy complications
TD172-193.5
Alkanesulfonic Acids
Perfluorooctanoic acid
Environmental Pollutants
Female
medicine.symptom
Caprylates
Adult
medicine.medical_specialty
National Health and Nutrition Examination Survey
Renal function
Perfluoroalkyl acids
Kidney function
Internal medicine
Diabetes mellitus
medicine
Diabetes Mellitus
Albuminuria
Humans
0105 earth and related environmental sciences
021110 strategic, defence & security studies
business.industry
Diabetes anemia
Public Health, Environmental and Occupational Health
Environmental Exposure
medicine.disease
Environmental sciences
Endocrinology
chemistry
Sulfonic Acids
business
Decanoic Acids
Biomarkers
Subjects
Details
- ISSN :
- 10902414
- Volume :
- 208
- Database :
- OpenAIRE
- Journal :
- Ecotoxicology and environmental safety
- Accession number :
- edsair.doi.dedup.....e06ab7d1dc40327989ddbfd21cf404e9