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Urolithiasis associated with topiramate
- Source :
- International Brazilian Journal of Urology, Vol 30, Iss 1, Pp 29-31 (2004), International braz j urol, Volume: 30, Issue: 1, Pages: 29-31, Published: FEB 2004, International braz j urol v.30 n.1 2004, International Braz J Urol, Sociedade Brasileira de Urologia (SBU), instacron:SBU
- Publication Year :
- 2004
- Publisher :
- Sociedade Brasileira de Urologia, 2004.
-
Abstract
- OBJECTIVE: Topiramate is a sulfamate-substituted monosaccharide anticonvulsant used as adjunctive therapy for intractable refractory seizures. It is report a case of topiramate-induced urolithiasis. CASE REPORT: A 35-year-old man presented with acute, right-sided, colicky flank pain. He denied hematuria or dysuria. He was in use of phenytoin, risperidone, phenobarbital, and topiramate. The total daily dose of topiramate was 375 mg. A CT scan showed a 7 x 1 mm curvilinear density at the right ureterovesical junction with proximal hydrouretronephrosis. He was managed with rigid ureteroscopic stone extraction and the calculus metabolic analysis revealed the stone was composed of carbonate apatite (70%), calcium oxalate dihydrate (20%), and calcium oxalate monohydrate (10%). COMMENTS: The present case typifies many features of topiramate-induced urolithiasis. Those who care for patients with urinary stone disease should be aware of this association.
- Subjects :
- Phenytoin
Topiramate
Adult
Male
medicine.medical_specialty
Urology
medicine.medical_treatment
Fructose
lcsh:RC870-923
Seizures
medicine
Dysuria
Humans
Adverse effect
acids
Risperidone
business.industry
urolithiasis
lcsh:Diseases of the genitourinary system. Urology
Surgery
Abdominal Pain
Anticonvulsant
Ureterovesical Junction
Acute Disease
anticonvulsants
adverse effects
Phenobarbital
Urinary Calculi
medicine.symptom
business
metabolism
medicine.drug
Subjects
Details
- Language :
- English
- ISSN :
- 16776119 and 16775538
- Volume :
- 30
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- International Brazilian Journal of Urology
- Accession number :
- edsair.doi.dedup.....e04e552bea56103a14a32397db9f3db6