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Atherosclerosis Imaging
- Source :
- Circulation: Cardiovascular Imaging. 2:150-160
- Publication Year :
- 2009
- Publisher :
- Ovid Technologies (Wolters Kluwer Health), 2009.
-
Abstract
- Despite the epidemiological insights from the Framingham Study1 in the early 1950s and the resulting significant advances in the diagnosis and management of coronary heart disease (CHD), it remains the leading cause of death in the United States. In part, this is because sudden cardiac death is the first presentation of CHD in 50% of men and 64% of women2,3 and, therefore, the only available strategy for reducing mortality in these patients is primary prevention. This is the target population for atherosclerosis imaging, which has been proposed as a strategy for the earlier and more accurate identification of individuals at risk for CHD so that lifesaving preventive strategies can be more optimally targeted in those at risk. Current guidelines for primary prevention recommend initial assessment and risk stratification based on traditional risk factors (eg, the Framingham Risk Score [FRS] in the United States and the Systemic Coronary Risk Evaluation in Europe), followed by goal-directed therapy as necessary to modify those risk factors.4 However, these traditional prevention strategies can be inadequate, as cardiovascular events do occur in patients without known risk or in low and intermediate risk groups in whom an aggressive treatment strategy would not be indicated. This is highlighted by a study of 222 young adults (men ≤55 years and women ≤65 years) without known prior CHD, hospitalized for acute myocardial infarction, of whom 70% were in a low-risk category with a 10-year risk of CHD
- Subjects :
- medicine.medical_specialty
Coronary Artery Disease
Coronary Angiography
Sudden cardiac death
Risk Factors
Epidemiology
medicine
Humans
Radiology, Nuclear Medicine and imaging
Myocardial infarction
Risk factor
Young adult
Intensive care medicine
National Cholesterol Education Program
Ultrasonography
Cause of death
Framingham Risk Score
business.industry
Calcinosis
Prognosis
medicine.disease
Carotid Arteries
Practice Guidelines as Topic
Medical emergency
Tomography, X-Ray Computed
Tunica Intima
Tunica Media
Cardiology and Cardiovascular Medicine
business
Subjects
Details
- ISSN :
- 19420080 and 19419651
- Volume :
- 2
- Database :
- OpenAIRE
- Journal :
- Circulation: Cardiovascular Imaging
- Accession number :
- edsair.doi.dedup.....e00a9122bef95427d9e91c238f9d0028