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Metabolic syndrome and hidradenitis suppurativa: epidemiological, molecular, and therapeutic aspects
- Source :
- International Journal of Dermatology. 61:1175-1186
- Publication Year :
- 2021
- Publisher :
- Wiley, 2021.
-
Abstract
- Hidradenitis suppurativa (HS) is a chronic, suppurative condition of the pilosebaceous unit. Patients suffering from HS demonstrate a molecular profile in keeping with a state of systemic inflammation and are often found to fit the criteria for a diagnosis of metabolic syndrome (MetS). In this paper, we review the literature with regards to established data on the prevalence of MetS in HS patients and revise the odds ratio of comorbid disease. Furthermore, we attempt to draw parallels between inflammatory pathways in HS and MetS and evaluate how convergences may explain the risk of comorbid disease, necessitating the need for multidisciplinary care.
- Subjects :
- Inflammation
Metabolic Syndrome
medicine.medical_specialty
business.industry
Pilosebaceous unit
MEDLINE
Dermatology
Odds ratio
medicine.disease
Systemic inflammation
Hidradenitis Suppurativa
Internal medicine
Epidemiology
Odds Ratio
Prevalence
medicine
Humans
Hidradenitis suppurativa
Molecular Profile
Metabolic syndrome
medicine.symptom
business
Subjects
Details
- ISSN :
- 13654632 and 00119059
- Volume :
- 61
- Database :
- OpenAIRE
- Journal :
- International Journal of Dermatology
- Accession number :
- edsair.doi.dedup.....dff0bd9ece9fdda7ad61f030391ca925