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Mortality in patients with diabetic foot ulcer: a retrospective study of 513 cases from a single Centre in the Northern Territory of Australia
- Source :
- BMC Endocrine Disorders, BMC Endocrine Disorders, Vol 19, Iss 1, Pp 1-7 (2019)
- Publication Year :
- 2019
- Publisher :
- Springer Science and Business Media LLC, 2019.
-
Abstract
- Background Diabetic foot ulcers (DFU) are a common problem in longstanding diabetes. However, mortality outcomes in Australian patients with DFU are still unclear. Methods All patients with DFU presenting for the first time to the Multi-Disciplinary Foot Clinic (MDFC) at Royal Darwin Hospital, Northern Territory Australia, between January 2003 and June 2015 were included in this study. These patients were followed until 2017, or death. Individual patient data was extracted from hospital and primary care information systems. Kaplan-Meier survival curves were developed. The association between various risk factors and mortality was analysed using Cox regression. Results In total 666 subjects were screened, and 513 were included in the final analysis. Of these subjects, 247 were Indigenous and 266 were non-Indigenous. The median follow-up period was 5.8 years (IQR, 3.1–9.8). The mean age at inclusion was 59.9 ± 12.3 years and 62.8% were males. The majority (93.6%) had type 2 diabetes and the median diabetes duration was 7 years (IQR, 3–12). There were 199 deaths, with a 5-year-mortality rate of 24.6%, and a 10-year-mortality rate of 45.4%. The mean age at death was 64.6 ± 11.8 years. In a multivariate analysis, the following variables were associated with mortality (adjusted HR, 95% CI): age 1.04 (1.02–1.05, P
- Subjects :
- Male
medicine.medical_specialty
Endocrinology, Diabetes and Metabolism
030209 endocrinology & metabolism
Diabetic foot ulcer
Comorbidity
Kaplan-Meier Estimate
Type 2 diabetes
lcsh:Diseases of the endocrine glands. Clinical endocrinology
Amputation, Surgical
03 medical and health sciences
Diabetes mellitus
0302 clinical medicine
Diabetes complications
Risk Factors
Cause of Death
Internal medicine
Ethnicity
Northern Territory
Risk of mortality
medicine
Humans
030212 general & internal medicine
Risk factor
Survival analysis
Aged
Retrospective Studies
lcsh:RC648-665
business.industry
General Medicine
Middle Aged
medicine.disease
Diabetic foot
Diabetic Foot
Female
business
Research Article
Follow-Up Studies
Kidney disease
Subjects
Details
- ISSN :
- 14726823
- Volume :
- 19
- Database :
- OpenAIRE
- Journal :
- BMC Endocrine Disorders
- Accession number :
- edsair.doi.dedup.....df9cf32e30c58339e2b671a5fafe807f