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Lewis Acid Catalyzed Reaction of Arylvinylidenecyclopropanes with Ethyl (Arylimino)acetates: A Facile Synthetic Protocol for Pyrrolidine and 1,2,3,4-Tetrahydroquinoline Derivatives

Authors :
Min Shi
Jian-Mei Lu
Source :
Organic Letters. 9:1805-1808
Publication Year :
2007
Publisher :
American Chemical Society (ACS), 2007.

Abstract

[reaction: see text] A number of pyrrolidine and 1,2,3,4-tetrahydroquinoline derivatives are prepared selectively in moderate to good yields by the reaction of arylvinylidenecyclopropanes 1 with ethyl (arylimino)acetates 2 in the presence of Lewis acid depending on the electronic nature both of 2 and R1 or R2 aromatic groups of 1.

Details

ISSN :
15237052 and 15237060
Volume :
9
Database :
OpenAIRE
Journal :
Organic Letters
Accession number :
edsair.doi.dedup.....df870000b85bb85bafbd383e3d2db04a
Full Text :
https://doi.org/10.1021/ol070501q