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Effect of cold exposure of the rabbit on the subsequent performance of its isolated ear artery with respect to temperature
- Source :
- Irish journal of medical science. 144(1)
- Publication Year :
- 2016
-
Abstract
- New Zealand white rabbits were exposed to an environmental temperature of either 20°C (control) or 5°C (cold-exposure) for periods of from one to six weeks. Ear skin temperature was around 30°C in the control environment and fell to around 15°C in the cold environment. Compared with control arteries, ear arteries from cold-exposed animals tended to have a lower optimal temperature for responses to injected noradrenaline (NOR). At 37°C, responses of control arteries exceeded those of cold-exposed arteries; at 12°C the situation was reversed. A similar “cross-over” effect was observed with responses to electrical stimulation (ES). However, in both groups of arteries, responses to ES were better preserved than were responses to NOR at low temperatures, possibly because cooling interfered with uptake into neuronal stores of NOR released by ES, thus allowing more NOR to reach the arterial muscle at these low temperatures.
- Subjects :
- medicine.medical_specialty
Human ear
Time Factors
Cold exposure
Stimulation
Cross Reactions
Body Temperature
Norepinephrine
Environmental temperature
Hypothermia, Induced
Internal medicine
medicine
Animals
New zealand white
Ear, External
Neurons
business.industry
Skin temperature
General Medicine
Arteries
Environmental Exposure
Electric Stimulation
Cold Temperature
Endocrinology
Anesthesia
Rabbits
business
Skin Temperature
Subjects
Details
- ISSN :
- 00211265
- Volume :
- 144
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Irish journal of medical science
- Accession number :
- edsair.doi.dedup.....df17b37c0a8bee18aa00660eb0f2c3ef