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Xenorhabdus stockiae KT835471-mediated feasible biosynthesis of metal nanoparticles for their antibacterial and cytotoxic activities
- Publication Year :
- 2017
- Publisher :
- Taylor & Francis, 2017.
-
Abstract
- In this study, extracellular metabolites of symbiotic bacteria Xenorhabdus stockiae (KT835471) was employed for the synthesis of silver (XsAgNPs) and gold nanoparticles (XsAuNPs). Synthesized NPs were characterized using high throughput instrumentation which confirms the generation of stable, crystalline XsAgNPs and XsAuNPs with the mean size of 14 ± 6 and 14 ± 5, respectively. Further, the NPs exhibits an excellent bactericidal effect against six different pathogens. On the other hand, NPs displayed an outstanding anticancer activity against human lung adenocarcinoma epithelial cells (A549). Therefore, the present study strongly suggests that metal NPs encrusted with functional bio-moieties can be used for different biomedical applications.
- Subjects :
- 0301 basic medicine
Silver
Materials science
Stereochemistry
education
Biomedical Engineering
Metal Nanoparticles
Pharmaceutical Science
Medicine (miscellaneous)
Antineoplastic Agents
Apoptosis
02 engineering and technology
medicine.disease_cause
Xenorhabdus
Metal
03 medical and health sciences
chemistry.chemical_compound
Biosynthesis
Extracellular
medicine
Humans
Cytotoxic T cell
Metal nanoparticles
technology, industry, and agriculture
Xenorhabdus stockiae
General Medicine
respiratory system
021001 nanoscience & nanotechnology
Anti-Bacterial Agents
030104 developmental biology
chemistry
Biochemistry
A549 Cells
Colloidal gold
visual_art
visual_art.visual_art_medium
Feasibility Studies
Gold
0210 nano-technology
Biotechnology
Symbiotic bacteria
Subjects
Details
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....defac7efea87dcc4e3f4afdf4afc9ff6
- Full Text :
- https://doi.org/10.6084/m9.figshare.4599961.v1