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Scalable nanophotonic neural probes for multicolor and on-demand light delivery in brain tissue
- Source :
- Nanotechnology. 32(26)
- Publication Year :
- 2020
-
Abstract
- Neural probes are in vivo brain-invasive devices that record and manipulate neural circuits using electricity, light, or drugs. The capability to shine distinct wavelengths and control their respective output locations for activation or deactivation of specific groups of neurons is desirable but remains unachieved. Here, we discuss our probe’s capability to deliver two independently controllable wavelengths (450 and 655 nm) in the location(s) of interest using nanophotonic directional couplers and ring resonators. These nanophotonics are scalable to dozens of outputs without significantly increasing the device’s lateral dimensions. Furthermore, they are entirely passive and thus do not require electrical input that results in heat generation. Besides, we integrate a high number of electrodes for a simultaneous neural activity readout. Thus, we overcome the challenges associated with multicolor illumination for neural devices by exploiting the capability of miniaturizable, passive probes to deliver two different frequencies in several areas of interest. These devices open the path towards investigating the in vivo electrical signal propagation under the individual or simultaneous activation or inhibition of distinct brain regions.
- Subjects :
- Materials science
Optical Phenomena
Nanophotonics
Bioengineering
Ring resonator
02 engineering and technology
Optogenetics
010402 general chemistry
01 natural sciences
Directional coupler
Resonator
On demand
Biological neural network
Nanotechnology
General Materials Science
Computer Simulation
Electrical and Electronic Engineering
Electrodes
Neurons
Wavelength demultiplexing
business.industry
Mechanical Engineering
Lasers
Brain
Neural probes
General Chemistry
021001 nanoscience & nanotechnology
0104 chemical sciences
Mechanics of Materials
Heat generation
Scalability
Optoelectronics
Power dividers and directional couplers
0210 nano-technology
business
Subjects
Details
- ISSN :
- 13616528
- Volume :
- 32
- Issue :
- 26
- Database :
- OpenAIRE
- Journal :
- Nanotechnology
- Accession number :
- edsair.doi.dedup.....dee2851032f022ef5b582aa95da591c0