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Imaging in Differentiating Cerebral Toxoplasmosis and Primary CNS Lymphoma With Special Focus on FDG PET/CT
- Source :
- American Journal of Roentgenology. 216:157-164
- Publication Year :
- 2021
- Publisher :
- American Roentgen Ray Society, 2021.
-
Abstract
- OBJECTIVE. The purpose of this article is to present a brief review of literature evaluating different imaging modalities with special focus on 18F-FDG PET/CT in differentiating cerebral toxoplasmosis and primary CNS lymphoma. CONCLUSION. Differentiating cerebral toxoplasmosis and primary CNS lymphoma is crucial in the care of patients with HIV infection. Delayed diagnosis can lead to considerable morbidity and mortality. The reference standard for diagnosis is biopsy and histopathologic examination. Biopsy has disadvantages due to its invasive nature and associated complications. Noninvasive imaging can be an alternative to biopsy for differentiation of toxoplasmosis and primary CNS lymphoma. Despite advances in MRI techniques, prophylaxis of opportunistic infection, and treatment of HIV infection, clinical situations continue to arise in which the diagnosis is not clear. In these instances, molecular imaging can be helpful.
- Subjects :
- medicine.medical_specialty
Lymphoma
Focus (geometry)
Opportunistic infection
030218 nuclear medicine & medical imaging
Diagnosis, Differential
03 medical and health sciences
0302 clinical medicine
Primary CNS Lymphoma
Fluorodeoxyglucose F18
Positron Emission Tomography Computed Tomography
Biopsy
Humans
Medicine
Radiology, Nuclear Medicine and imaging
PET-CT
medicine.diagnostic_test
Brain Neoplasms
business.industry
General Medicine
medicine.disease
Toxoplasmosis
Cerebral toxoplasmosis
Toxoplasmosis, Cerebral
030220 oncology & carcinogenesis
Radiology
Radiopharmaceuticals
Molecular imaging
business
Subjects
Details
- ISSN :
- 15463141 and 0361803X
- Volume :
- 216
- Database :
- OpenAIRE
- Journal :
- American Journal of Roentgenology
- Accession number :
- edsair.doi.dedup.....deaabfda36694774ebbc720c825b5dc5