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Pharmacologic Management of Acutely Agitated Pediatric Patients
- Source :
- Pediatric Drugs. 13:1-10
- Publication Year :
- 2011
- Publisher :
- Springer Science and Business Media LLC, 2011.
-
Abstract
- Acute agitation is a state of behavioral dyscontrol that requires intervention. Medications available in rapid delivery formats are frequently administered to treat acute agitation, either as a chemical restraint or on a voluntary basis. Prior to initiating treatment, the etiology of agitation must be evaluated. In choosing a medication, general pharmacologic principles should be followed. Medication should be selected based on the underlying cause in conjunction with weighing the risks, benefits, and side effects of medications. There are three classes of medications administered to children and adolescents to treat agitation: antihistamines, benzodiazepines, and antipsychotics. The most concerning short-term side effects of antipsychotics are their adverse neurologic effects, neuroleptic malignant syndrome, and prolonged corrected QT interval. Compared with typical antipsychotics, atypical antipsychotics have a more favorable short-term side effect profile.
- Subjects :
- Olanzapine
medicine.medical_specialty
Adolescent
Side effect
medicine.drug_class
Histamine Antagonists
Atypical antipsychotic
Behavioral Symptoms
Benzodiazepines
Chemical restraint
Humans
Medicine
Pharmacology (medical)
Ziprasidone
Child
Intensive care medicine
Psychomotor Agitation
Risperidone
business.industry
medicine.disease
Neuroleptic malignant syndrome
Anesthesia
Acute Disease
Pediatrics, Perinatology and Child Health
Aripiprazole
business
Antipsychotic Agents
medicine.drug
Subjects
Details
- ISSN :
- 11745878
- Volume :
- 13
- Database :
- OpenAIRE
- Journal :
- Pediatric Drugs
- Accession number :
- edsair.doi.dedup.....dea2c9b778459d704e3628cc47c48156