Proliferating Cells Conserve Nitrogen to Support Growth

Authors :: Ralph J. DeBerardinis
Source :: Cell metabolism. 23(6)
Publication Year :: 2016
Abstract: Glutamate provides a large intracellular pool of carbon and nitrogen. Coloff et al. (2016) find that proliferating cells shift from a nitrogen-wasting to a nitrogen-sparing mode of glutamate catabolism, highlighting the exquisite tethering of proliferative signals to metabolism.

Tools