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Very preterm neonates receiving 'aggressive' nutrition and early nCPAP had similar long-term respiratory outcomes as term neonates
- Source :
- Pediatric Research
- Publication Year :
- 2019
- Publisher :
- Nature Publishing Group US, 2019.
-
Abstract
- Backround The impact of the consistent implementation of “aggressive” nutrition by means of intensive early neonatal nutritional support up to 40–44 weeks postmenstrual age and the use of nasal continuous positive airway pressure (nCPAP) within the first hour of life on the respiratory function of very premature neonates (VPN) at school age is unclear. Method Respiratory function was evaluated in 108 VPN and 70 term controls. Growth, frequency of lower respiratory tract infections, re-hospitalization, and spirometry were recorded up to 8–10 years of age. Comparison was carried out between the two study groups. Results There was no significant difference in forced expiratory volume in 1 s and forced vital capacity at 8 years of age, and also in lower respiratory tract infections and re-hospitalization due to them, up to 8 years of age between preterm and term neonates. No significant difference was found in spirometry measurements neither between premature neonates with and without BPD nor between the two subgroups of preterms and term neonates. Conclusion “Aggressive” nutrition, persistent nCPAP use, and their impact on early postnatal growth probably positively affect the respiratory function of our study population. These very encouraging results need to be confirmed by larger studies.
- Subjects :
- Spirometry
Male
Pediatrics
medicine.medical_specialty
Vital capacity
medicine.medical_treatment
Nutritional Status
03 medical and health sciences
0302 clinical medicine
030225 pediatrics
medicine
Humans
Respiratory function
Continuous positive airway pressure
Respiratory system
Child
Clinical Research Article
Respiratory Distress Syndrome, Newborn
Respiratory tract infections
medicine.diagnostic_test
Continuous Positive Airway Pressure
business.industry
Postmenstrual Age
Infant, Newborn
Respiratory Function Tests
Infant, Extremely Premature
Pediatrics, Perinatology and Child Health
Population study
Female
business
030217 neurology & neurosurgery
Diet Therapy
Subjects
Details
- Language :
- English
- ISSN :
- 15300447 and 00313998
- Volume :
- 86
- Issue :
- 6
- Database :
- OpenAIRE
- Journal :
- Pediatric Research
- Accession number :
- edsair.doi.dedup.....de5393b589945674f20e7f099650344b