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Synthesis and photophysical properties of iron-carbonyl complex–coumarin conjugates as potential bimodal IR–fluorescent probes
- Source :
- Tetrahedron Letters, Tetrahedron Letters, Elsevier, 2016, 57 (45), pp.4991-4996. 〈http://www.sciencedirect.com/science/article/pii/S0040403916312849〉. 〈10.1016/j.tetlet.2016.09.091〉, Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual), Universidade de São Paulo (USP), instacron:USP, Tetrahedron Letters, Elsevier, 2016, 57 (45), pp.4991-4996. ⟨10.1016/j.tetlet.2016.09.091⟩
- Publication Year :
- 2016
- Publisher :
- HAL CCSD, 2016.
-
Abstract
- International audience; An expedient synthesis of the first examples of iron-carbonyl complex-coumarin conjugates is reported. 7-Amino/7-hydroxycoumarin derivatives have been readily derivatized through an easily implemented single-step reaction involving the tricarbonyl(eta(5)-cyclohexadienyl)iron(1+) cation [(C6H7)Fe(CO)(3)](+). The scope and limitations of this N-/O-alkylation reaction were also investigated. The fluorescence properties of these novel metal-carbonyl complexes have been studied and support their further use as valuable building blocks in the design of bimodal contrast agents for combined vibrational and fluorescence imaging. (C) 2016 Elsevier Ltd. All rights reserved
- Subjects :
- Iron-carbonyl complexes
Fluorescence-lifetime imaging microscopy
Infrared
imaging scompi
010402 general chemistry
Photochemistry
01 natural sciences
Biochemistry
Fluorescence
active-site
Electron transfer
chemistry.chemical_compound
Dual imaging probes
COMPOSTOS ORGÂNICOS
Coumarins
[ CHIM.ORGA ] Chemical Sciences/Organic chemistry
Drug Discovery
tricarbonyliron complexes
organic-synthesis
biology
[CHIM.ORGA]Chemical Sciences/Organic chemistry
010405 organic chemistry
Organic Chemistry
Active site
flavonoid derivatives
electron-transfer
Coumarin
cations
0104 chemical sciences
core multimodal probe
fluorogenic probes
chemistry
biology.protein
Organic synthesis
Conjugate
organoiron complexes
Subjects
Details
- Language :
- English
- ISSN :
- 00404039
- Database :
- OpenAIRE
- Journal :
- Tetrahedron Letters, Tetrahedron Letters, Elsevier, 2016, 57 (45), pp.4991-4996. 〈http://www.sciencedirect.com/science/article/pii/S0040403916312849〉. 〈10.1016/j.tetlet.2016.09.091〉, Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual), Universidade de São Paulo (USP), instacron:USP, Tetrahedron Letters, Elsevier, 2016, 57 (45), pp.4991-4996. ⟨10.1016/j.tetlet.2016.09.091⟩
- Accession number :
- edsair.doi.dedup.....ddec0b9b2e67fe72f7bc8da687a487a9