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Additional B-cell malignancies in patients with chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL)
- Source :
- Leukemialymphoma. 61(7)
- Publication Year :
- 2020
-
Abstract
- Family and migration studies suggest a genetic risk of developing chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL). We hypothesized that CLL patients have an increased risk of additional clonally unrelated B-cell malignancies. To test this, we studied 467 CLL patients (2743 person-years (PYs)) at a single institution over 17 years. The incidence rate (IR) of any additional B-cell lymphoid malignancy was 10.9 per 1000 PYs (
- Subjects :
- Cancer Research
Lymphoma, B-Cell
Chronic lymphocytic leukemia
Lymphocytic lymphoma
03 medical and health sciences
0302 clinical medicine
immune system diseases
Risk Factors
hemic and lymphatic diseases
Medicine
Humans
In patient
Genetic risk
neoplasms
B cell
B-Lymphocytes
business.industry
Incidence
Hematology
medicine.disease
Leukemia, Lymphocytic, Chronic, B-Cell
Increased risk
medicine.anatomical_structure
Oncology
030220 oncology & carcinogenesis
Diffuse large cell lymphoma
Cancer research
Hodgkin lymphoma
business
030215 immunology
Subjects
Details
- ISSN :
- 10292403
- Volume :
- 61
- Issue :
- 7
- Database :
- OpenAIRE
- Journal :
- Leukemialymphoma
- Accession number :
- edsair.doi.dedup.....dd89cb0297f3c9adeb6391af7a2679f3