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Research Advances on the Adverse Effects of Nanomaterials in a Model Organism, Caenorhabditis elegans
- Source :
- Environmental Toxicology and Chemistry. 40:2406-2424
- Publication Year :
- 2021
- Publisher :
- Wiley, 2021.
-
Abstract
- Along with the rapid development of nanotechnology, the bio-safety assessment of nanotechnology products, including nanomaterials, becomes more and more important. Nematode Caenorhabditis elegans (C. elegans) is a valuable model organism that has been widely used in the field of biology because of their excellent advantages, including low cost, small size, short life span, and highly conservative genomes with vertebral animals. In recent years, the number of nanotoxicological researches using C. elegans is persistently growing. According to these available studies, this review classified the adverse effects of nanomaterials in C. elegans into systematic, cellular and molecular toxicity, and focused on summarizing and analyzing the underlying mechanisms of metal, metal oxide and non-metallic nanomaterials causing toxic effects in C. elegans. The findings in this review provided an insight in further studies on assessing bio-safety of nanomaterials in the ecosystem using C. elegans. This article is protected by copyright. All rights reserved.
- Subjects :
- Nematode caenorhabditis elegans
ved/biology
Health, Toxicology and Mutagenesis
ved/biology.organism_classification_rank.species
Environmental exposure
Computational biology
Biology
biology.organism_classification
Short life
Nanostructures
Nanotoxicology
Animals
Environmental Chemistry
Caenorhabditis elegans
Model organism
Ecosystem
Subjects
Details
- ISSN :
- 15528618 and 07307268
- Volume :
- 40
- Database :
- OpenAIRE
- Journal :
- Environmental Toxicology and Chemistry
- Accession number :
- edsair.doi.dedup.....dd846a52800fc015c106b89a5c17f71c