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Seroprevalence of Helicobacter pylori infection and its related risk factors in symptomatic patients in southern Ethiopia
- Source :
- BMC Research Notes
- Publication Year :
- 2014
- Publisher :
- BioMed Central, 2014.
-
Abstract
- Background Helicobacter pylori is the main etiology of peptic ulcers and chronic gastritis. Various studies showed that blood type ‘O’ is more common among patients with peptic ulcer. The aim of this study was to determine the seroprevalence of H. pylori antibodies and its relationship with ABO/Rhesus blood groups, age, sex and residence of symptomatic patients in southern Ethiopia. Methods A cross-sectional study was conducted in a total of 408 consecutive patients with upper abdominal complaints at Hawassa University Hospital from October 2012 to January 2013. Data on demographic factors was collected from all participants using questionnaires. Blood samples were also collected and tested for ABO and Rh blood group phenotype using hemagglutination test and for anti-H. pylori antibody (IgG) using two different ELISAs.. Results The overall seroprevalence of H. pylori infection was 83.3% (340/408), and it was significantly higher in rural (71.2%) compared to urban residents (28.8%) (p = 0.008). Participants with blood group AB, A, O, B, and Rh positive had H. pylori prevalence of 88.9, 84.2, 83.7, 80.9, and 83.5%, respectively. H. pylori infection was not significantly influenced by age, sex, occupation, educational status and ABO/ Rh status (p >0.05). Conclusion The high seroprevalence of H. pylori infection especially among rural residents calls for immediate intervention measures so that its clinical consequences could be minimized. ABO/Rh blood group was not found to be associated with H. pylori infection.
- Subjects :
- Adult
Male
medicine.medical_specialty
Adolescent
Peptic
Chronic gastritis
Seroprevalence
General Biochemistry, Genetics and Molecular Biology
ABO Blood-Group System
Helicobacter Infections
Young Adult
Age Distribution
Risk Factors
Seroepidemiologic Studies
Internal medicine
ABO blood group system
medicine
Humans
Aged
Medicine(all)
Blood type
Aged, 80 and over
Rh-Hr Blood-Group System
biology
Helicobacter pylori
Biochemistry, Genetics and Molecular Biology(all)
business.industry
General Medicine
ABO blood groups
Middle Aged
biology.organism_classification
medicine.disease
Immunology
Etiology
Female
Ethiopia
business
Rh blood group system
Research Article
Subjects
Details
- Language :
- English
- ISSN :
- 17560500
- Volume :
- 7
- Database :
- OpenAIRE
- Journal :
- BMC Research Notes
- Accession number :
- edsair.doi.dedup.....dd6ae5e086d0bb3fdd944997139109e1