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Altered myelin maturation in four year old children born very preterm

Authors :
Margot J. Taylor
Julia M. Young
Marlee M. Vandewouw
John G. Sled
Manohar Shroff
Source :
NeuroImage: Clinical, Vol 21, Iss, Pp-(2019), NeuroImage : Clinical
Publication Year :
2019
Publisher :
Elsevier, 2019.

Abstract

Children born very preterm (VPT<br />Highlights • Very preterm children have widespread decreased MTR in white matter. • T1-w/T2-w ratio measures showed consistent white matter alterations. • T1-w/T2-w ratio was also reduced in subcortical, occipital and temporal regions. • MTR and T1-w/T2-w were correlated throughout the brain. • MTR and T1-w/T2-w correlated with developmental assessments.

Subjects

Subjects :
Male
T2-w, T2-weighted
MTR, magnetization transfer ratio
ROI, region of interest
Audiology
lcsh:RC346-429
Myelin
Child Development
0302 clinical medicine
Sup.LFT, superior longitudinal fasciculus temporal part
C.CG, cingulum cingulate gyrus
FA, fractional anisotropy
VPT, Very preterm
Myelin Sheath
FT, full term
Magnetization transfer ratio
T1-weighted/T2-weighted ratio
medicine.diagnostic_test
DK, Desikan-Killiany
Putamen
05 social sciences
VMI, Visual-Motor Integration
Brain
Gestational age
F.MIN, forceps minor
Inf.LF, inferior longitudinal fasciculus
Diffusion Tensor Imaging
medicine.anatomical_structure
Neurology
Child, Preschool
Infant, Extremely Premature
lcsh:R858-859.7
Female
Myelin enhanced contrast
FSIQ, Full Scale Intelligence Quotients
medicine.medical_specialty
FDR, false discovery rate
ANCOVA, analysis of covariance
CS, corticospinal tract
Cognitive Neuroscience
F.MAJ, forceps major
TFCE, threshold-free cluster enhancement
lcsh:Computer applications to medicine. Medical informatics
Article
050105 experimental psychology
MT, magnetization transfer
White matter
03 medical and health sciences
Magnetic resonance imaging
Preterm
Region of interest
medicine
Humans
C.H, cingulum hippocampus
0501 psychology and cognitive sciences
Radiology, Nuclear Medicine and imaging
Effects of sleep deprivation on cognitive performance
lcsh:Neurology. Diseases of the nervous system
Inf.FOF, inferior fronto-occipital fasciculus
Full Term
T1-w, T1-weighted
business.industry
Infant, Newborn
CL, Core Language
Sup.LF, superior longitudinal fasciculus
TBSS, tract-based spatial statistics
UF, uncinate fasciculus
DTI, diffusion tensor imaging
Neurology (clinical)
Ant.TR, anterior thalamic radiation
business
GA, gestational age
MRI, magnetic resonance imaging
030217 neurology & neurosurgery

Details

Language :
English
ISSN :
22131582
Volume :
21
Database :
OpenAIRE
Journal :
NeuroImage: Clinical
Accession number :
edsair.doi.dedup.....dd1ea38961dd7f4e6db859166ee88efc