Experimental study of beam hardening artifacts in photon counting breast computed tomography

We are implementing an X-ray breast Computed Tomography (CT) system on the gantry of a dedicated single photon emission tomography system for breast Tc-99 imaging. For the breast CT system we investigated the relevance of the beam hardening artifact. We studied the use of a single photon counting silicon pixel detector (0.3 mm thick, 256 � 256 pixel, 55mm pitch, bump-bonded to the Medipix2 photon counting readout chip) as detector unit in our X-ray CT system. We evaluated the beam hardening ‘‘cupping’’ artifact using homogeneous PMMA slabs and phantoms up to 14 cm in diameter, used as uncompressed breast tissue phantoms, imaged with a tungsten anode tube at 80 kVp with 4.2 mm Al filtration. For beam hardening evaluation we used a bimodal energy model. The CT data show a ‘‘cupping’’ artifact going from 4% (4-cm thick material) to 18% (14-cm thick material). This huge artifacts is influenced by the low detection efficiency and the charge sharing effect of the silicon pixel detector. r 2007 Published by Elsevier B.V. PACS: 85.57.cp; 87.57.Q