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Morbid obesity is an independent risk factor for postoperative renal dysfunction in young adults: a review of the American College of Surgeons National Surgical Quality Improvement Program database
- Source :
- The American Journal of Surgery. 211:772-777
- Publication Year :
- 2016
- Publisher :
- Elsevier BV, 2016.
-
Abstract
- Little information exists on the acute effects of elective surgery on renal function. Our aim was to determine if obesity was an independent risk factor for postoperative renal complications (RCs).A total of 119,142 patients aged 18 to 35 years with body mass index (BMI) ≥18 kg/m(2) obtained from American College of Surgeons National Surgical Quality Improvement Project (2005 to 2010) were classified into standard BMI categories. Association between BMI and preoperative estimated glomerular filtration rate (eGFR; calculated using modification of diet in renal disease formula) was analyzed. Postoperative changes in eGFR and RCs were measured. Multivariate regression analysis was performed adjusting for all variables.Postoperatively, there was a reduction in eGFR among the overweight (-3.4 mL/min/1.73 m(2), P.001), obese class I (-3.9 mL/min/1.73 m(2), P = .001), and obese class II (-5.3 mL/min/1.73 m(2), P.001). The odds of any postoperative RC was significantly higher in obese class III patients (odds ratio = 2.01 95% confidence interval 1.07 to 3.76, P = .029).Results seen in patients with BMI greater than 40 indicate that BMI can serve as an independent predictor of RCs.
- Subjects :
- Adult
Male
medicine.medical_specialty
Adolescent
Renal function
Disease
030204 cardiovascular system & hematology
Overweight
03 medical and health sciences
Postoperative Complications
0302 clinical medicine
Risk Factors
Internal medicine
medicine
Humans
030212 general & internal medicine
Elective surgery
Young adult
Risk factor
business.industry
General Medicine
medicine.disease
Quality Improvement
Obesity
Obesity, Morbid
Surgery
Elective Surgical Procedures
Female
Kidney Diseases
medicine.symptom
business
Body mass index
Glomerular Filtration Rate
Subjects
Details
- ISSN :
- 00029610
- Volume :
- 211
- Database :
- OpenAIRE
- Journal :
- The American Journal of Surgery
- Accession number :
- edsair.doi.dedup.....dcf42b4cf46640c0e65ee288d2b7b682
- Full Text :
- https://doi.org/10.1016/j.amjsurg.2015.11.027