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Targetable nano-delivery vehicles to deliver anti-bacterial small acid-soluble spore protein (SASP) genes
- Source :
- Emerging Topics in Life Sciences. 5:637-641
- Publication Year :
- 2021
- Publisher :
- Portland Press Ltd., 2021.
-
Abstract
- Interest in phage-based therapeutics is increasing, at least in part due to the need for new treatment options for infections caused by antibiotic-resistant bacteria. It is possible to use wild-type (WT) phages to treat bacterial infections, but it is also possible to modify WT phages to generate therapeutics with improved features. Here, we will discuss features of Phico Therapeutics’ SASPject technology, which modifies phages for use as targetable nano-delivery vehicles (NDV), to introduce antibacterial Small Acid Soluble Spore Protein (SASP) genes into specific target bacteria.
- Subjects :
- Spores
biology
Chemistry
medicine.drug_class
viruses
Antibiotics
Treatment options
Bacterial Infections
biology.organism_classification
General Biochemistry, Genetics and Molecular Biology
Anti-Bacterial Agents
Spore
Microbiology
Bacteriophage
Antibiotic resistance
Genes, Bacterial
medicine
Humans
Bacteriophages
Anti bacterial
General Agricultural and Biological Sciences
Gene
Bacteria
Subjects
Details
- ISSN :
- 23978562 and 23978554
- Volume :
- 5
- Database :
- OpenAIRE
- Journal :
- Emerging Topics in Life Sciences
- Accession number :
- edsair.doi.dedup.....dce4b522e6f5d0910ed762d02d95c478