Additional file 5: of Elusive sources of variability of dystrophin rescue by exon skipping

Dystrophin protein expression detected by IF and WB after 7Â days of PMO delivery. Four mice were treated with one high dose of PMO (800Â mg/kg) and sacrificed at 7Â days. Tibialis anterior muscles were dissected and analyzed by IF and WB. We observed low levels of dystrophin protein by both quantification methods as compared to saline-treated mice. (PDF 265 kb)