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Cytotoxic limonoids from the root bark of Dictamnus angustifolius
- Source :
- Fitoterapia. 115
- Publication Year :
- 2016
-
Abstract
- Three novel limonoids, dictangustone G (1), dictangustone H (2), and dictangustone I (3) were isolated from the root bark of Dictamnus angustifolius. Their structures were elucidated on the basis of detailed spectroscopic analysis including UV, IR, HRESIMS, 1D and 2D NMR spectroscopic experiments. Compounds 1–3 were evaluated for their cytotoxic activities using Hela, A549, MCF7, and LN229 cell lines.
- Subjects :
- Limonins
Stereochemistry
010402 general chemistry
01 natural sciences
Plant Roots
HeLa
Cell Line, Tumor
Drug Discovery
Cytotoxic T cell
Humans
Dictamnus
Pharmacology
biology
Molecular Structure
010405 organic chemistry
Chemistry
General Medicine
biology.organism_classification
Antineoplastic Agents, Phytogenic
0104 chemical sciences
visual_art
visual_art.visual_art_medium
Plant Bark
Bark
Two-dimensional nuclear magnetic resonance spectroscopy
Subjects
Details
- ISSN :
- 18736971
- Volume :
- 115
- Database :
- OpenAIRE
- Journal :
- Fitoterapia
- Accession number :
- edsair.doi.dedup.....dccbe8eead3212b9f245c10d5cacc39c