Henoch-Schönlein Purpura with Posterior Reversible Encephalopathy Syndrome

Henoch-Schonlein purpura is a common small-vessel vasculitis that presents in children as nonthrombocytopenic, nontender, and palpable purpura, arthritis/arthralgia, and abdominal pain. Central nervous system involvement is a reported, but likely, under-recognized complication. We present an 8-year-old boy with Henoch-Schonlein purpura and posterior reversible encephalopathy syndrome, after proposed mechanism and treatment considerations.