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Cost‐Effectiveness of Surgical Weight‐Loss Interventions for Patients With Knee Osteoarthritis and Class III Obesity

Cost‐Effectiveness of Surgical Weight‐Loss Interventions for Patients With Knee Osteoarthritis and Class III Obesity

Authors :
Aleksandra M. Kostic
Valia P. Leifer
Yusi Gong
Malcolm K. Robinson
Jamie E. Collins
Tuhina Neogi
Stephen P. Messier
David J. Hunter
Faith Selzer
Lisa G. Suter
Jeffrey N. Katz
Elena Losina
Source :
Arthritis Care & Research. 75:491-500
Publication Year :
2022
Publisher :
Wiley, 2022.

Abstract

Class III obesity (body mass index [BMI] ≥40 kg/mWe used the Osteoarthritis Policy model to assess long-term clinical benefits, costs, and cost-effectiveness of RYGB and LSG. We derived model inputs for efficacy, costs, and complications associated with these treatments from published data. Primary outcomes included quality-adjusted life-years (QALYs), lifetime costs, and incremental cost-effectiveness ratios (ICERs), all discounted at 3%/year. This analysis was conducted from a health care sector perspective. We performed sensitivity analyses to evaluate uncertainty in input parameters.The usual care + RYGB strategy increased the quality-adjusted life expectancy by 1.35 years and lifetime costs by $7,209, compared to usual care alone (ICER = $5,300/QALY). The usual care + LSG strategy yielded less benefit than usual care + RYGB and was dominated. Relative to usual care alone, both usual care + RYGB and usual care + LSG reduced opioid use from 13% to 4%, and increased TKR usage from 30% to 50% and 41%, respectively. For cohorts with BMI between 38 and 41 kg/mRYGB offers good value among knee OA patients with BMI ≥40 kg/m

Subjects

Subjects :
Rheumatology

Details

ISSN :
21514658 and 2151464X
Volume :
75
Database :
OpenAIRE
Journal :
Arthritis Care & Research
Accession number :
edsair.doi.dedup.....dc825176a6d891c906b1dd2cd6594cbb
Full Text :
https://doi.org/10.1002/acr.24967