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Analysis of18F-fluorodeoxyglucose positron emission tomography findings in patients with pituitary lesions
- Source :
- The Korean Journal of Internal Medicine
- Publication Year :
- 2013
- Publisher :
- Korean Association of Internal Medicine, 2013.
-
Abstract
- Background/Aims: Although magnetic resonance imaging (MRI) is a good visual modality for the evaluation of pituitary lesions, it has limited value in the diagnosis of mixed nodules and some cystic lesions. We evaluated the usefulness of 18F-fluorodeoxyglucose positron emission tomography (FDG PET) for patients with pituitary lesions. Methods: 18F-FDG PET and MRI were performed simultaneously in 32 consecutive patients with pituitary lesions. The relationships between FDG uptake patterns in PET and MRI findings were analyzed. Results: Of 24 patients with piuitary adenomas, 19 (79.2%) showed increased uptake of 18F-FDG in the pituitary gland on PET scans. All patients with pituitary macroadenomas showed increased 18F-FDG uptake on PET scans. Meanwhile, only five (50%) of the 10 patients with pituitary microadenomas showed positive PET scans. Interestingly, of two patients with no abnormal MRI findings, one showed increased 18F-FDG uptake on PET. For positive 18F-FDG uptake, maximum standardized uptake values (SUVmax) > 2.4 had 94.7% sensitivity and 100% specificity. In addition, SUVmax increased in proportion to the size of pituitary adenomas. Most cystic lesions did not show 18F-FDG uptake on PET scans. Consclusions: About 80% of pituitary adenomas showed positivity on PET scans, and SUVmax was related to the size of the adenomas. PET may be used as an ancillary tool for detection and differentiation of pituitary lesions.
- Subjects :
- Adenoma
Adult
Male
Pituitary gland
medicine.medical_specialty
Adolescent
Pituitary neoplasm
Fluorodeoxyglucose positron emission tomography
Young Adult
Fluorodeoxyglucose F18
Predictive Value of Tests
Humans
Medicine
Pituitary Neoplasms
In patient
Aged
Aged, 80 and over
medicine.diagnostic_test
business.industry
Magnetic resonance imaging
Middle Aged
medicine.disease
Magnetic Resonance Imaging
Tumor Burden
medicine.anatomical_structure
Pituitary
Positron emission tomography
Pituitary Gland
Positron-Emission Tomography
Predictive value of tests
Female
Original Article
Radiology
Radiopharmaceuticals
business
Nuclear medicine
Subjects
Details
- ISSN :
- 20056648 and 12263303
- Volume :
- 28
- Database :
- OpenAIRE
- Journal :
- The Korean Journal of Internal Medicine
- Accession number :
- edsair.doi.dedup.....dc219b24f820968659e9c81534dd0473