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Rapid Viral Symbiogenesis via Changes in Parasitoid Wasp Genome Architecture

Authors :
Tyler J. Simmonds
Gaelen R. Burke
Barbara J. Sharanowski
Scott M. Geib
Source :
Molecular Biology and Evolution. 35:2463-2474
Publication Year :
2018
Publisher :
Oxford University Press (OUP), 2018.

Abstract

Viral genome integration provides a complex route to biological innovation that has rarely but repeatedly occurred in one of the most diverse lineages of organisms on the planet, parasitoid wasps. We describe a novel endogenous virus in braconid wasps derived from pathogenic alphanudiviruses. Limited to a subset of the genus Fopius, this recent acquisition allows an unprecedented opportunity to examine early endogenization events. Massive amounts of virus-like particles (VLPs) are produced in wasp ovaries. Unlike most endogenous viruses of parasitoid wasps, the VLPs do not contain DNA, translating to major differences in parasitism-promoting strategies. Rapid changes include genomic rearrangement, loss of DNA processing proteins, and wasp control of viral gene expression. These events precede the full development of tissue-specific viral gene expression observed in older associations. These data indicate that viral endogenization can rapidly result in functional and evolutionary changes associated with genomic novelty and adaptation in parasitoids.

Details

ISSN :
15371719 and 07374038
Volume :
35
Database :
OpenAIRE
Journal :
Molecular Biology and Evolution
Accession number :
edsair.doi.dedup.....dc1533af8e1047b0d94a54e56ab8345b
Full Text :
https://doi.org/10.1093/molbev/msy148