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Development of a European Organization for Research and Treatment of Cancer questionnaire module to assess the quality of life of ovarian cancer patients in clinical trials
- Source :
- European Journal of Cancer. 37:47-53
- Publication Year :
- 2001
- Publisher :
- Elsevier BV, 2001.
-
Abstract
- A questionnaire was developed, according to the European Organization for Research and Treatment of Cancer (EORTC) published guidelines, to supplement the EORTC quality of life questionnaire-core 30 (QLQ-C30) to assess the quality of life (QL) of women with ovarian cancer treated in clinical trials. The provisional 28-item module, OV28, assesses abdominal symptoms; peripheral neuropathy; other chemotherapy side-effects; hormonal symptoms; body image; attitude to disease and treatment; and sexual functioning. The first 24 items of the module (excluding sexual functioning) were included in a UK multicentre trial (SCOTROC). The trial data were used for preliminary scaling analysis. Two problematic items were identified. When these were treated as single items along with the 'other chemotherapy side-effects' the instrument showed excellent scale properties. Mean scale scores discriminated between trial patients pre- and on chemotherapy. This is a promising tool for assessing the QL of women with ovarian cancer. The EORTC international field study (Protocol 15982) to assess more fully the psychometric properties of the OV28 is well underway.
- Subjects :
- Cancer Research
medicine.medical_specialty
medicine.medical_treatment
Antineoplastic Agents
Disease
Quality of life
Surveys and Questionnaires
medicine
Humans
Ovarian Neoplasms
Gynecology
Clinical Trials as Topic
Chemotherapy
business.industry
Sexual functioning
Cancer
Middle Aged
medicine.disease
humanities
Clinical trial
Oncology
Quality of Life
Physical therapy
Female
Abdominal symptoms
business
Ovarian cancer
Subjects
Details
- ISSN :
- 09598049
- Volume :
- 37
- Database :
- OpenAIRE
- Journal :
- European Journal of Cancer
- Accession number :
- edsair.doi.dedup.....dbc96e1d9ca23a20edba3f825c3b2ffe
- Full Text :
- https://doi.org/10.1016/s0959-8049(00)00369-5