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Prognosis in Patients Hospitalized With Permanent and Nonpermanent Atrial Fibrillation in Heart Failure
- Source :
- The American Journal of Cardiology. 113:1189-1195
- Publication Year :
- 2014
- Publisher :
- Elsevier BV, 2014.
-
Abstract
- Atrial fibrillation (AF) and heart failure (HF) frequently coexist and are associated with an increased mortality. This study evaluated the prognosis of permanent and nonpermanent AF in patients with both AF and HF. All AF patients seen in our institution were identified and followed up. We included 1,906 patients suffering from AF and HF: 839 patients (44%) had preserved left ventricular ejection fraction (LVEF) and 1,067 patients (56%) had decreased LVEF; 1,056 patients (55%) had nonpermanent AF and 850 patients (45%) had permanent AF. During a median follow-up of 1.9 years (interquartile range 0.3 to 5.0), 377 patients died, 462 were readmitted for HF, and 200 had stroke or thromboembolic events. In patients with decreased LVEF, the rate of death was similar in patients with permanent or nonpermanent AF. In patients with preserved LVEF, permanent AF was associated with a higher risk of death and a higher risk of HF hospitalization. Stroke risk did not differ with permanent AF whatever the LVEF. NYHA functional class was an independent predictor of death (risk ratio [RR] = 1.33, 95% confidence interval [CI] 1.12 to 1.59, p = 0.001), as was permanent AF (RR = 1.79, 95%CI 1.32 to 2.42, p = 0.0002). Permanent AF (RR = 1.52, 95% CI 1.20 to 1.93, p = 0.0006) was also an independent predictor of readmission for HF. In conclusion, in patients with AF and HF, the risk of admission for HF and risk of death were higher when AF was permanent, particularly in patients with preserved LVEF. Stroke risk did not differ according to the pattern of AF, whatever the LVEF.
- Subjects :
- Male
medicine.medical_specialty
Ventricular Function, Left
Sex Factors
Risk Factors
Interquartile range
Thromboembolism
Internal medicine
Atrial Fibrillation
medicine
Humans
Hospital Mortality
cardiovascular diseases
Stroke
Aged
Retrospective Studies
Heart Failure
Ejection fraction
business.industry
Incidence
Age Factors
Stroke Volume
Atrial fibrillation
Retrospective cohort study
Stroke volume
Prognosis
medicine.disease
Hospitalization
Survival Rate
Relative risk
Heart failure
Cardiology
Female
France
Cardiology and Cardiovascular Medicine
business
Follow-Up Studies
Subjects
Details
- ISSN :
- 00029149
- Volume :
- 113
- Database :
- OpenAIRE
- Journal :
- The American Journal of Cardiology
- Accession number :
- edsair.doi.dedup.....db82af738db8fed18e807c2d93e3e490