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Leptospira infection in people in the city of Durango, Mexico: a cross sectional study
- Source :
- The Journal of International Medical Research
- Publication Year :
- 2021
- Publisher :
- SAGE Publications, 2021.
-
Abstract
- Objective To determine the seroprevalence of Leptospira immunoglobulin (Ig)G and IgM antibodies and its association with the characteristics of the study population from the northern Mexican city of Durango, Mexico. Methods Through a cross-sectional study design, inhabitants of Durango City, Mexico were surveyed between June 2018 and November 2018. Serum samples from the subjects were analysed for anti- Leptospira IgG and IgM antibodies using commercially available enzyme-linked immunosorbent assays. Sociodemographic, clinical, behavioural and housing characteristics were recorded. Data were analysed by bivariate and multivariate analyses. Results The study enrolled 413 people, of which 124 (30.0%) and 137 (33.2%) were positive for anti- Leptospira IgG antibodies and anti- Leptospira IgM antibodies, respectively. Multivariate analysis showed that Leptospira seropositivity was associated with professional occupation, alcohol consumption, ill clinical status, memory impairment and a history of surgery. Conclusions This is the first study to report the seroepidemiology of Leptospira infection in an urban general population in the north of Mexico. The seroprevalence of Leptospira infection found was higher than those previously reported in Mexican studies.
- Subjects :
- medicine.medical_specialty
Mexican City
Cross-sectional study
Igm antibody
animal diseases
030231 tropical medicine
Biochemistry
03 medical and health sciences
0302 clinical medicine
Leptospira
Environmental health
Epidemiology
Medicine
Seroprevalence
030212 general & internal medicine
Mexico
biology
seroprevalence
business.industry
Biochemistry (medical)
Cell Biology
General Medicine
biology.organism_classification
bacterial infections and mycoses
biology.protein
Population study
bacteria
epidemiology
Antibody
business
urban
Retrospective Clinical Research Report
Subjects
Details
- Language :
- English
- ISSN :
- 14732300 and 03000605
- Volume :
- 49
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- The Journal of International Medical Research
- Accession number :
- edsair.doi.dedup.....db691f148ae726e9a782465fae17e091