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Reading positional codes with fMRI: Problems and solutions
- Source :
- PLoS ONE, PLoS ONE, Vol 12, Iss 5, p e0176585 (2017)
- Publication Year :
- 2018
- Publisher :
- PLOS, 2018.
-
Abstract
- Neural mechanisms which bind items into sequences have been investigated in a large body of research in animal neurophysiology and human neuroimaging. However, a major problem in interpreting this data arises from a fact that several unrelated processes, such as memory load, sensory adaptation, and reward expectation, also change in a consistent manner as the sequence unfolds. In this paper we use computational simulations and data from two fMRI experiments to show that a host of unrelated neural processes can masquerade as sequence representations. We show that dissociating such unrelated processes from a dedicated sequence representation is an especially difficult problem for fMRI data, which is almost exclusively the modality used in human experiments. We suggest that such fMRI results must be treated with caution and in many cases the assumed neural representation might actually reflect unrelated processes.
- Subjects :
- Physiology
Vision
Computer science
Social Sciences
Monkeys
Brain mapping
Diagnostic Radiology
Learning and Memory
0302 clinical medicine
Cognition
Animal Cells
Reading (process)
Functional Magnetic Resonance Imaging
Medicine and Health Sciences
Psychology
media_common
Mammals
Neurons
Motor Neurons
Sequence
Brain Mapping
Multidisciplinary
medicine.diagnostic_test
Radiology and Imaging
05 social sciences
Representation (systemics)
Brain
Magnetic Resonance Imaging
Electrophysiology
Vertebrates
Medicine
Sensory Perception
Cellular Types
Algorithms
Research Article
Cognitive psychology
Primates
Imaging Techniques
media_common.quotation_subject
Science
Neuroimaging
Models, Psychological
Research and Analysis Methods
Rodents
050105 experimental psychology
03 medical and health sciences
Reward
Diagnostic Medicine
Memory
medicine
Animals
Humans
0501 psychology and cognitive sciences
Computer Simulation
Structure (mathematical logic)
Sensory Adaptation
Modality (human–computer interaction)
Organisms
Biology and Life Sciences
Magnetic resonance imaging
Cell Biology
Neurophysiology
Cellular Neuroscience
Amniotes
Mental Recall
Cognitive Science
Functional magnetic resonance imaging
030217 neurology & neurosurgery
Neuroscience
Subjects
Details
- Database :
- OpenAIRE
- Journal :
- PLoS ONE, PLoS ONE, Vol 12, Iss 5, p e0176585 (2017)
- Accession number :
- edsair.doi.dedup.....db65aa8264025d9704b2e2ea303e4bb5
- Full Text :
- https://doi.org/10.17863/cam.21323