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Safety and efficacy of SARS-Cov2 neutralizing monoclonal antibodies after stem cell transplant or CAR-T cell infusion

Authors :
Elisabetta Metafuni
Antonella Cingolani
Massimo Fantoni
Patrizia Chiusolo
Sabrina Giammarco
Federica Sorà
Eugenio Galli
Stefan Hohaus
Francesco D’Alò
Silvia Bellesi
Elena Maiolo
Eleonora Alma
Luca Laurenti
Idanna Innocenti
Francesco Autore
Maria Assunta Limongiello
Rosaria Santangelo
Simona Marchetti
Rosalba Ricci
Simona Sica
Source :
Hematological oncology.
Publication Year :
2022

Abstract

Severe acute respiratory syndrome coronavirus 2 caused a worldwide pandemia starting from March 2020. A major concern was for hematological patients, which resulted to be defenseless due to their impaired immune system and the difficulty to obtain a valid serological response to vaccination. A promising weapon is the use of anti-SARS-CoV2 monoclonal antibodies in patients with mild COVID-19 infection at high risk of progression into severe disease. Here, we reported our preliminary results of anti-SARS-CoV2 monoclonal antibodies administration for COVID-19 occurred after cell therapy. This article is protected by copyright. All rights reserved.

Details

ISSN :
10991069
Database :
OpenAIRE
Journal :
Hematological oncology
Accession number :
edsair.doi.dedup.....db34773f50ee69ab432152c4986226ed