Single-cell transcriptomics reveals hidden information in trypanosomatids

Made available in DSpace on 2022-04-28T19:47:08Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-01-01 Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Dixenic parasites often encounter environmental extremes during the transition from vector to host. Preadapted transmission stages overcome these challenges to promote parasites' survival and ensure life cycle progression. Recently, Vigneron et al. and Briggs et al. used single-cell transcriptomics to investigate developmental stage specific gene expression patterns during parasite differentiation. DNA Replication and Repair Laboratory Department of Chemical and Biological Sciences Institute of Biosciences São Paulo State University (UNESP) Faculty of Medicine of Ribeirão Preto University of São Paulo The Wellcome Centre for Integrative Parasitology Institute of Infection Immunity and Inflammation University of Glasgow DNA Replication and Repair Laboratory Department of Chemical and Biological Sciences Institute of Biosciences São Paulo State University (UNESP) FAPESP: 2019/10753-2 FAPESP: 2020/01883-7 FAPESP: 2020/10277-3 FAPESP: 2020/16480-5