Back to Search
Start Over
The Hospital Water Environment as a Reservoir for Carbapenem-Resistant Organisms Causing Hospital-Acquired Infections—A Systematic Review of the Literature
- Source :
- Clinical Infectious Diseases. 64:1435-1444
- Publication Year :
- 2017
- Publisher :
- Oxford University Press (OUP), 2017.
-
Abstract
- Over the last 20 years there have been 32 reports of carbapenem-resistant organisms in the hospital water environment, with half of these occurring since 2010. The majority of these reports have described associated clinical outbreaks in the intensive care setting, affecting the critically ill and the immunocompromised. Drains, sinks, and faucets were most frequently colonized, and Pseudomonas aeruginosa the predominant organism. Imipenemase (IMP), Klebsiella pneumoniae carbapenemase (KPC), and Verona integron-encoded metallo-β-lactamase (VIM) were the most common carbapenemases found. Molecular typing was performed in almost all studies, with pulse field gel electrophoresis being most commonly used. Seventy-two percent of studies reported controlling outbreaks, of which just more than one-third eliminated the organism from the water environment. A combination of interventions seems to be most successful, including reinforcement of general infection control measures, alongside chemical disinfection. The most appropriate disinfection method remains unclear, however, and it is likely that replacement of colonized water reservoirs may be required for long-term clearance.
- Subjects :
- 0301 basic medicine
Microbiology (medical)
medicine.medical_specialty
Disease reservoir
biology
Klebsiella pneumoniae
Pseudomonas aeruginosa
business.industry
030106 microbiology
Outbreak
Carbapenem-resistant enterobacteriaceae
biochemical phenomena, metabolism, and nutrition
030501 epidemiology
biology.organism_classification
medicine.disease_cause
03 medical and health sciences
Infectious Diseases
Intensive care
medicine
Water environment
Infection control
0305 other medical science
Intensive care medicine
business
Subjects
Details
- ISSN :
- 15376591 and 10584838
- Volume :
- 64
- Database :
- OpenAIRE
- Journal :
- Clinical Infectious Diseases
- Accession number :
- edsair.doi.dedup.....daf09e2b802ad97d557e473c7c67dca9