Determinação por RMN das configurações relativas e conformações de alcalóides oxindólicos isolados de Uncaria guianensis

Submitted by Guilherme Lemeszenski (guilherme@nead.unesp.br) on 2013-08-22T18:48:33Z No. of bitstreams: 1 S0100-40422004000600007.pdf: 221665 bytes, checksum: c447ca6529b7c3940429d633e2f49c75 (MD5) Made available in DSpace on 2013-08-22T18:48:33Z (GMT). No. of bitstreams: 1 S0100-40422004000600007.pdf: 221665 bytes, checksum: c447ca6529b7c3940429d633e2f49c75 (MD5) Previous issue date: 2004-12-01 Made available in DSpace on 2013-09-30T19:38:31Z (GMT). No. of bitstreams: 2 S0100-40422004000600007.pdf: 221665 bytes, checksum: c447ca6529b7c3940429d633e2f49c75 (MD5) S0100-40422004000600007.pdf.txt: 21180 bytes, checksum: 716ba7827e843aeb26f1337177d0921f (MD5) Previous issue date: 2004-12-01 Submitted by Vitor Silverio Rodrigues (vitorsrodrigues@reitoria.unesp.br) on 2014-05-20T14:21:04Z No. of bitstreams: 2 S0100-40422004000600007.pdf: 221665 bytes, checksum: c447ca6529b7c3940429d633e2f49c75 (MD5) S0100-40422004000600007.pdf.txt: 21180 bytes, checksum: 716ba7827e843aeb26f1337177d0921f (MD5) Made available in DSpace on 2014-05-20T14:21:04Z (GMT). No. of bitstreams: 2 S0100-40422004000600007.pdf: 221665 bytes, checksum: c447ca6529b7c3940429d633e2f49c75 (MD5) S0100-40422004000600007.pdf.txt: 21180 bytes, checksum: 716ba7827e843aeb26f1337177d0921f (MD5) Previous issue date: 2004-12-01 Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) Phytochemical studies with leaves of Uncaria guianensis resulted in the isolation of the oxindole alkaloids isomitraphylline (1), 3-isoajmalicine (2) mitraphylline (3), and isomitraphylinic acid (4). Structural assignments of these alkaloids, including relative configurations and conformations, were performed through spectral data and physical properties. 1D and 2D homonuclear and heteronuclear NMR spectroscopy was a valuable tool for the establishment of the relative stereochemistry of those compounds. Universidade Estadual Paulista Instituto de Química Universidade Estadual Paulista Instituto de Botânica Seção de Fisiologia e Bioquímica de Plantas Universidade Estadual Paulista Instituto de Química Universidade Estadual Paulista Instituto de Botânica Seção de Fisiologia e Bioquímica de Plantas