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Brief Report: A High Rate of β7+ Gut-Homing Lymphocytes in HIV-Infected Immunological Nonresponders is Associated With Poor CD4 T-Cell Recovery During Suppressive HAART
- Source :
- Journal of Acquired Immune Deficiency Syndromes (1999)
- Publication Year :
- 2016
-
Abstract
- Supplemental Digital Content is Available in the Text.<br />Objective: Correlation between GALT homing markers on lymphocytes and the low blood CD4 T-cell reconstitution in immunological nonresponders (INRs) has been studied. Design: Thirty-one INRs, 19 immunological responders (IRs), and 12 noninfected controls were enrolled in this study. INRs were defined by an undetectable plasma viral load RNA less than 40 copies per milliliter and CD4+ T-cell count
- Subjects :
- 0301 basic medicine
CD4-Positive T-Lymphocytes
INR
lymphocytes
HIV integration
Receptors, Lymphocyte Homing
HIV Infections
Biology
Immunophenotyping
03 medical and health sciences
0302 clinical medicine
Intestinal mucosa
Antiretroviral Therapy, Highly Active
Cytotoxic T cell
Humans
Pharmacology (medical)
gut homing
Intestinal Mucosa
Lymphocyte homing receptor
Early Detection of Cancer
α4β7 integrin
Basic and Translational Science
HIV
Viral Load
Anus Neoplasms
Flow Cytometry
030104 developmental biology
Infectious Diseases
Immunology
ComputingMethodologies_DOCUMENTANDTEXTPROCESSING
Disease Progression
HIV-1
RNA, Viral
Viral load
CD8
030215 immunology
Homing (hematopoietic)
Subjects
Details
- ISSN :
- 19447884
- Volume :
- 72
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Journal of acquired immune deficiency syndromes (1999)
- Accession number :
- edsair.doi.dedup.....daaefd0c4d9a164de237bbb6e38b64d8