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Factors associated with clinical interpretation of tracheal wash fluid from dogs with respiratory disease: 281 cases (2012‐2017)
- Source :
- Journal of Veterinary Internal Medicine, Journal of Veterinary Internal Medicine, Vol 35, Iss 2, Pp 1073-1079 (2021)
- Publication Year :
- 2021
- Publisher :
- Wiley, 2021.
-
Abstract
- Background Clinicians face several dilemmas regarding tracheal washes (TWs) for the diagnosis of respiratory disease, including method and prediction of bacterial growth from cytology results. Objective To compare cytology and culture of endotracheal and transtracheal washes and identify factors associated with discordancy and bacterial growth. Animals Two hundred forty‐five dogs with respiratory disease. Methods Retrospective study. Tracheal wash submissions were included if cellularity was sufficient for cytologic interpretation and aerobic cultures were performed. Collection technique, cytology, bacterial growth, and antibiotic history were analyzed. Results Fewer transtracheal specimens (9/144, 6.3%) were excluded for hypocellularity than endotracheal (28/174, 16.1%); otherwise, results were similar and were combined. Of 281 specimens with cellularity sufficient for interpretation, 97 (34.5%) had bacteria on cytology and 191 (68.0%) had bacterial growth. Cytology positive/culture negative discordancy was uncommon (8/97, 8%). Cytology negative/culture positive discordancy was frequent (102/184, 55.4%), but occurred less often (28/184, 14.2%) when only 1+ growth or greater was considered positive. Oropharyngeal contamination was associated with bacterial growth, but not discordancy. No association was found between antibiotic administration and bacterial growth. Conclusions and Clinical Importance Endotracheal wash fluid, in particular, should be screened for gross mucus or turbidity to maximize the likelihood of an adequate specimen. Otherwise, endotracheal and transtracheal specimens were similar. Presence of bacteria on cytology was a good predictor of any growth, while their absence was a good predictor of the absence of growth of 1+ or more. Recent antibiotic usage should not discourage TW culture if there is compelling reason to avoid delay.
- Subjects :
- medicine.medical_specialty
040301 veterinary sciences
medicine.drug_class
Respiratory Tract Diseases
Antibiotics
endotracheal
Standard Article
030204 cardiovascular system & hematology
Bacterial growth
Gastroenterology
antibiotics
0403 veterinary science
03 medical and health sciences
Dogs
0302 clinical medicine
Internal medicine
Cytology
medicine
Animals
Dog Diseases
Retrospective Studies
transtracheal
lcsh:Veterinary medicine
Bacteria
General Veterinary
business.industry
Respiratory disease
Retrospective cohort study
04 agricultural and veterinary sciences
medicine.disease
Mucus
Standard Articles
Anti-Bacterial Agents
Trachea
Hypocellularity
aerobic culture
Respiratory
lcsh:SF600-1100
SMALL ANIMAL
Culture negative
business
Subjects
Details
- ISSN :
- 19391676 and 08916640
- Volume :
- 35
- Database :
- OpenAIRE
- Journal :
- Journal of Veterinary Internal Medicine
- Accession number :
- edsair.doi.dedup.....daa1c8a1dd86c8fac2f70c455b216ed4