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Sarcopenia is associated with an increased risk of advanced colorectal neoplasia
- Source :
- International Journal of Colorectal Disease. 32:557-565
- Publication Year :
- 2016
- Publisher :
- Springer Science and Business Media LLC, 2016.
-
Abstract
- Although sarcopenia is associated with an increased risk for mortality after the curative resection of colorectal cancer, its influence on the development of advanced colonic neoplasia remains unclear. This study included 1270 subjects aged 40 years or older evaluated with first-time screening colonoscopy at Seoul National University Boramae Health Care Center from January 2010 to February 2015. Skeletal muscle mass was measured with a body composition analyzer (direct segmental multifrequency bioelectrical impedance analysis method). Multiple logistic regression analysis was performed to determine whether sarcopenia is associated with advanced colorectal neoplasia. Of 1270 subjects, 139 (10.9%) were categorized into the sarcopenia group and 1131 (89.1%) into the non-sarcopenia group. In the non-sarcopenia group, 55 subjects (4.9%) had advanced colorectal neoplasia. However, in the sarcopenia group, 19 subjects (13.7%) had advanced colorectal neoplasia, including 1 subject with invasive colorectal cancer (0.7%). In addition, subjects with sarcopenia had a higher prevalence of advanced adenoma (P
- Subjects :
- Adenoma
Adult
Male
Oncology
Sarcopenia
medicine.medical_specialty
Colorectal cancer
Colonoscopy
Gastroenterology
03 medical and health sciences
0302 clinical medicine
Risk Factors
Internal medicine
Prevalence
Humans
Medicine
Muscle, Skeletal
Aged
Neoplasm Staging
medicine.diagnostic_test
business.industry
Confounding
Organ Size
Odds ratio
Middle Aged
Hepatology
musculoskeletal system
medicine.disease
Confidence interval
030220 oncology & carcinogenesis
Regression Analysis
Female
030211 gastroenterology & hepatology
Colorectal Neoplasms
Tomography, X-Ray Computed
business
human activities
Bioelectrical impedance analysis
Subjects
Details
- ISSN :
- 14321262 and 01791958
- Volume :
- 32
- Database :
- OpenAIRE
- Journal :
- International Journal of Colorectal Disease
- Accession number :
- edsair.doi.dedup.....da9797a0c8ea38358d140be5c5c3366b