The cellular composition of uterine fluid in IUD users - a quantitative study

The cellular composition of uterine fluid was studied quantitatively in 75 IUD users and 48 non-users. In the IUD group the number of granulocytes was increased about 300 times above that of the non-IUD group, whereas the numbers of mononuclear phagocytic cells and lymphocytes were increased by a factor of 30. Endometrial glandular cells were not quantitatively affected by the presence of an IUD. Granulocytes constituted nearly two-thirds and mononuclear phagocytic cells nearly one-third of the total cell count in the IUD group. Mast cells wee found more frequently and eosinophilia occurred more often in the uterine fluid of IUD users.